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Hydralazine causes dilation of the walls of blood vessels and is sometimes used to treat hypertension.
Hydralazine is known to deplete the blood of vitamin B
. Taking B
supplements may prevent or reverse side effects of the medication.
Coenzyme Q10 (CoQ10)
There is some evidence that hydralazine might impair the body's ability to manufacture the substance coenzyme Q
This suggests (but definitely does not prove) that taking CoQ
supplements may produce a beneficial effect.
relaxes blood vessels and might have unpredictable effects if combined with hydralazine.
1Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634.
2Goodman L and Gilman A. The pharmacological basis of therapeutics, 9th ed. Hardman J, et al (eds.). New York: McGraw-Hill, 1996: 1562.
Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q
-enzymes by clinically used anti-hypertensive drugs.
Res Commun ChemPathol Pharmacol
12(3): 533–40, 1975.