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  • Definition

    Acute epididymitis is an inflammation of the epididymis. This is a structure that surrounds and attaches to each testicle. It is shaped like a tube. The epididymis helps transport and store sperm cells.
    Chronic epididymitis causes discomfort or pain in the epididymis. It can last for 3 months or longer. This type is less common.
    The Epididymis
    si2188 testicle
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  • Causes

    This condition is most often caused by a bacterial infection. For example:
    Other causes include:
    • Injury
    • Viral infections, such as mumps
    • Genital abnormalities
    • Treatment with amiodarone, a heart rhythm drug
    • Chemotherapy to treat bladder cancer
    • Vasectomy
  • Risk Factors

    Only men can develop this condition. It affects men age 15-30 with sexually transmitted bacteria begin a common cause. It also affects men over 60 with urinary tract infections being a common cause.
    Other factors that increase the risk of epididymitis include:
    • Infection of the genitourinary tract—urethra, bladder, kidney, prostate, or testicle
    • Narrowing of the urethra
    • Use of a urethral catheter
    • Infrequent emptying of the bladder
    • Recent surgery or instrumentation of the genitourinary tract—especially prostate removal
    • Birth defects of the genitourinary tract
    • Unprotected sex
    • Disease that affects the immune system
    Children and newborns can get epididymitis.
  • Symptoms

    Symptoms usually develop within 1 day. These include:
    • Pain in the testicles
    • Sudden redness or swelling of the scrotum
    • Hardness, a lump, and/or soreness in the affected testicle
    • Tenderness in the unaffected testicle
    • Groin pain
    • Chills
    • Fever
    • Inflammation of the urethra
    • Pain during intercourse or ejaculation
    • Pain and/or burning during urination
    • Increased pain while having a bowel movement
    • Lower abdominal discomfort
    • Discharge from the penis
  • Diagnosis

    You will be asked about your symptoms and medical history. A physical exam will be done.
    Your bodily fluids may be tested. This can be done with:
    • Urinalysis
    • Urine culture
    • Culture or other test of discharge from penis
    • Blood tests
    Images may be taken of your scrotum. This can be done with ultrasound.
  • Treatment

    Treatment is essential to prevent the infection from worsening. Treatment may include:
    • Bed rest—This keeps the testicles from moving and promotes healing. You may need bed rest until the swelling goes away.
    • Antibiotics—You will be given antibiotics to treat a bacterial infection. Many cases of epididymitis are caused by sexually transmitted bacteria. Chlamydia is one of the most common. If you have an STD , your partner(s) will also need treatment.
    • Oral anti-inflammatory medication—This includes drugs like ibuprofen to help reduce swelling.
    • Scrotal elevation and support—You may need to wear an athletic supporter for several weeks.
    • Warm baths—Taking baths can ease the pain and help relieve swelling.
    • Surgery—This may be needed in severe cases that keep coming back.
  • Prevention

    The following steps can help decrease your risk:
    • Practice safe sex. Protect yourself from STDs by using condoms .
    • Empty your bladder as soon as you feel the need.

    National Kidney Foundation

    Urology Care Foundation


    Health Canada

    The Kidney Foundation of Canada


    Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2010. MMWR. 2010;59(No. RR-12):1-110.

    Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guide: 2006. MMWR. 2006;55. Centers for Disease Control and Prevention website. Available at: Accessed August 31, 2015.

    Hori S, Sengupta A, et al. Long-term outcome of epididymectomy for the management of chronic epididymal pain. J Urol. 2009 Oct;182(4):1407-1412.

    Santillanes G, Gausche-Hill M, et al. Are antibiotics necessary for pediatric epididymitis? Pediatr Emerg Care. 2011 Feb 19.

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