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CMV Infection

(Cytomegalovirus)
  • Definition

    Cytomegalovirus (CMV) is a common infection caused by a type of herpes virus. It can cause swollen lymph glands, fever, and fatigue. Most people with CMV do not show symptoms of infection and are not aware they have it. A CMV infection usually occurs in young adults. The virus then remains in your body for the rest of your life. It is often in a sleeping state but can be activated by stressful situations.
    CMV infections rarely causes health problems except for people with compromised immune systems.
    Babies who are not born yet are also at risk for congenital CMV.
    The Lymphatic Organs
    The Lymphatic Organs
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  • Causes

    The virus is passed between people through body fluids. CMV can be passed during:
    • Kissing
    • Sexual intercourse
    • Breastfeeding
    • Changing the diaper of an infected infant
  • Risk Factors

    This virus is so common throughout the US that everyone is considered at risk for CMV. People with the highest risk of getting this virus include:
    • Children and childcare providers in day care and preschool—due to frequent exposure to bodily fluids
    • People with suppressed or impaired immune systems including people with:
  • Symptoms

    The virus does not cause any symptoms when it is inactive. The virus may be activated because of stressful situations, medication, illness, or reduced immunity. Symptoms of the activated virus include:
    People with suppressed or impaired immune systems can also develop:
  • Diagnosis

    CMV infection is not often diagnosed because the virus rarely produces symptoms. If CMV is suspected, the doctor may look for signs of the infection in blood or fluid samples. A biopsy may also be done on organs that are affected.
  • Treatment

    Most people infected with CMV will not need a specific treatment. Treatment may be needed if the virus is reactivated and you have a weakened immune system.
    Antiviral medications may be used for people who have an organ transplant or suppressed immune system. These medications do not cure CMV but can decrease the symptoms and duration of the illness.
  • Prevention

    While there is no definitive way to prevent CMV, but there are some measures that can decrease your chance of the infection:
    • Wash your hands frequently.
    • Properly dispose of diapers.
    • Do not share glasses or eating utensils.
    • Avoiding intimate contact with people known to have the CMV infection.
    • Practice safe sex.
  • RESOURCES

    Centers for Disease Control and Preventio http://www.cdc.gov

    Infectious Diseases Society of America http://www.idsociety.org

    CANADIAN RESOURCES

    Herpes Guide http://www.herpesguide.ca

    Public Health Agency of Canada http://www.phac-aspc.gc.ca

    References

    Cytomegalovirus. American Association of Family Physicians website. Available at: http://familydoctor.org/familydoctor/en/diseases-conditions/cytomegalovirus.html. Updated July 2013. Accessed June 19, 2014.

    Cytomegalovirus (CMV) infection. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated June 16, 2014. Accessed June 19, 2014.

    Cytomegalovirus and congenital CMV infection. Centers for Disease Control and Prevention (CDC) website. Available at: http://www.cdc.gov/cmv/index.html. Updated July 28, 2010. Accessed June 19, 2014.

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